November 25, 2021

CUENCA, Patricia and RAMIREZ, Vanessa. Aberraciones cromosómicas en trabajadoras expuestas a plaguicidas. Rev. biol. trop [online]. , vol, n.3, pp. ABERRACIONES. CROMOSÓMICAS. Dra. Laura Santana Díaz Médico Genetista. Morfología y estructura de los cromosomas humanos. Cariotipo Constitución. PDF | On Jan 1, , Fernado N. Dulout and others published Análisis de aberraciones cromosómicas en anafase-telofase de la mitosis. I. Acción clastogénica.

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Al contrario, varias publicaciones han detectado diferencias entre grupos de fumadores y no fumadores: Measurement of micronuclei in lymphocytes. The micronuclei scoring is performed on binucleated cells and the starting sample may vary, although most studies are performed on peripheral blood lymphocytes. Fenech M, Crott JW. Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei.

Environ Mol Mutagen ; Cell division, chromosomal damage and micronucleus formation in peripheral lymphocytes of healthy donors: The micronucleus assay in human lymphocytes: Cytogenetic biomonitoring of Spanish greenhouse workers exposed to pesticides: Factors contributing to chromosome damage in lymphocytes of cigarette smokers.

Micronuclei and chromatid buds are the result of related genotoxic events. Contributions to the development of a protocol suitable for regulatory submissions from an examination of 16 chemicals with different mechanisms of action and different levels of activity.

The micronuclei assay is considered a practical, universally validated and technically feasible protocol which is useful to evaluate the genetic instability induced by genotoxic agents. Int J Cancer ; The cytokinesis-block micronucleus technique: Zalacain 1L.


Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences. Micronucleus formation in peripheral-blood lymphocytes from smokers and the influence of alcohol- and tea-drinking habits. Sex chromosome loss, micronuclei, sister chromatid exchange and aging: Micronuclei in cytokinesis-blocked lymphocytes as an index of occupational exposure to alkylating cytostatic drugs.

Evaluation of micronuclei frequency aberarciones the cultured peripheral blood lymphocytes of cancer patients before and after radiation treatment.

Cancer Lett ; Micronuclei, nucleoplasmic bridges and nuclear buds induced in folic acid deficient human lymphocytes-evidence for breakage-fusion-bridge cycles in the cytokinesis-block micronucleus assay. Fenech M, Morley AA. Kirsch-Volders M, Fenech M.

Mutability of p53 hotspot codons to benzo a pyrene diol epoxide BPDE and the frequency of p53 mutations in nontumorous human lung. Contribution of sex, age, and lifestyle.

Antonio Bermudez – Google Scholar Citations

The position of the in vitro micronucleus test within the battery of screening for genotoxic potential determination and the regulatory guidelines. El recuento de MN se debe realizar sobre 1. High susceptibility to lung cancer analyzed in cromosoicas of combined genotypes of PIA1 and Mu-class glutathione S-transferase genes.

Effect of smoking habit on the frequency of micronuclei in human lymphocytes: Environ Toxicol Chem ; Influence of smoking habit on the frequency of micronuclei in human lymphocytes by the cytokinesis block method.

Jpn J Cancer Res ; Sister chromatid exchange and micronucleus frequency in human lymphocytes of 1, subjects in an Italian population: Micronucleus monitoring of a floriculturist population from western Liguria, Italy. Importance of detecting numerical aberracioness structural chromosome aberrations.


El ensayo de micronúcleos como medida de inestabilidad genética inducida por agentes genotóxicos

Ginseng reduces the micronuclei yield in lymphocytes after irradiation. Micronuclei in lymphocytes of young patients under antileukemic therapy. What do human aberrxciones contain? Clastogenic effect for cigarette smoking but not areca quid chewing as measured by micronuclei in exfoliated buccal mucosal cells. Chem Res Toxicol ; Norppa H, Falck GC. Chromosomal instability in amniocytes from fetuses of mothers who smoke.

A protocol for the in vitro micronucleus test.

Inhibition of oxidative DNA damage, 8-OHdG, and carbonyl contents in smokers treated with antioxidants vitamin E, vitamin C, beta-carotene and red ginseng. Micronuclei frequencies in hospital workers occupationally exposed to low levels of ionizing radiation: The in cromoosomicas micronucleus technique. Micronucleus induction in gill cells of green-lipped mussels Perna viridis exposed to mixtures of polycyclic aromatic hydrocarbons and chlorinated pesticides.

There are several abegraciones able to modify the number of micronuclei present in a given cell, among them are age, gender, vitamins, medical treatments, daily exposure to genotoxic agents, etc. The cytogenetic assay for the detection of micronuclei CBMN: Cancer Res ; The cytogenetic assay as a measure of genetic instability induced by genotoxic agents.

The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes. Mutat Res ; Hainaut P, Pfeifer GP.