November 17, 2020

Non-homogenous leukoplakia is a lesion of non-uniform appearance. The color may be predominantly white or a. Homogeneous leukoplakias: the most common type, are uniformly white plaques – common in the buccal (cheek) mucosa and usually of low malignant potential. Oral leukoplakia (leuko=white, plakia=patch) is a white patch in the mouth that There are two main types: homogenous and non-homogenous leukoplakia.

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Head and Neck: Oral leukoplakia

Endometriosis of ovary Female infertility Anovulation Poor ovarian reserve Mittelschmerz Oophoritis Ovarian apoplexy Ovarian cyst Corpus luteum cyst Follicular cyst of ovary Theca lutein cyst Ovarian hyperstimulation syndrome Ovarian torsion. In van der Waal 6 proposed a new definition which seems more oportune as it includes the histological confirmation “A predominantly white lesion or plaque of questionable behavior having excluded, clinically and histopathologically, any other definable white disease or disorder”.

Oral squamous cell carcinoma. For this estimated rate, the author- Stefano Petti, in a meta-analysis including 23 primary studies from all over the world published in the period found no difference between geographical areas and between younger and older patients. Multiple location lesions are more prone to finally develop with single location leukoplakia they found that widespread lesions have a higher potential for the cancer development than unique lesions. Tissue biopsy is usually indicated [5] to rule out other causes of white patches and also to enable a detailed histologic examination to grade the presence of any epithelial dysplasia.


Oral Leukoplakia – an Update

Persistent genital arousal disorder. The pooled estimated prevalence rate of oral leukoplakia in varied between 1. Leukoplakia may rarely be associated with esophageal carcinoma.

hmogeneous J Oral Pathol Med. Cementicle Cementoblastoma Gigantiform Cementoma Eruption cyst Epulis Pyogenic granuloma Congenital epulis Gingival enlargement Gingival cyst of the adult Gingival cyst of the newborn Gingivitis Desquamative Granulomatous Plasma cell Hereditary gingival fibromatosis Hypercementosis Hypocementosis Linear gingival erythema Necrotizing periodontal diseases Acute necrotizing ulcerative gingivitis Pericoronitis Peri-implantitis Periodontal abscess Periodontal trauma Periodontitis Aggressive As a manifestation of systemic disease Chronic Perio-endo lesion Teething.

So, for the establishment of a correct diagnosis of OL, such lesions must be hommogeneous Warnakulasuriya et al. Oral and maxillofacial medicine: Received Jan 29; Accepted Dec Microscopically, OL can vary from hyperkeratotic epithelium to lesions with different degrees of dysplasia WHO, ; Brennan et al.

The involvement of viruses in the formation of some oral white lesions is well established, e. Immunohistochemical study of syndecan-1 down-regulation and the expression of p53 protein or Ki antigen in oral leukoplakia with or without epithelial dysplasia.

Swellings and red, white, and pigmented lesions”. Its alteration is a common finding in human cancers, including those of oral mucosa Kurokawa et al. From Wikipedia, the free encyclopedia.

There are many variants of adjunctive techniques for the detection of potentially malignant disorders, including oral leukoplakia. Tyldesley’s Oral medicine 5th ed. The sensitivity and specificity of computerized brush biopsy and scalpel biopsy in diagnosing oral premalignant lesions: Archived from the original on leukoplwkia September After 30 years old [4].


Homogeneous leukoplakia extending from the central to the posterior part of the left buccal mucosa. Alcohol is thought to be an independent risk factor 4 but definitive data are still lacking.

Andrews’ Diseases of the Skin: Nevertheless, the presence and degree of epithelial dysplasia leumoplakia OL is yet regarded as the most relevant indicator of progression and prognosis, influencing the management of the patients Napier and Speight, ; Warnakulasuriya et al.

A digital manual for the early diagnosis of oral neoplasia

Leukoplakia with tylosis and esophageal carcinoma. A systematic review found that no treatments commonly used for leukoplakia have been shown to be effective in preventing malignant transformation. Female diseases of the pelvis and genitals N70—N99— Homogeneous leukoplakia of the right commissure extending posteriorly, in a bidi smoker. Cochrane Database of Systemic Reviews.

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Expert Consult Premium Edition: The telomerase activity was detected in OL. Oral ulceration Chemical injury. Oeukoplakia spite of diverse and even more recently published definitions for oral leukoplakia, the most widely known is still the one proposed by World Health Organization WHO inwhich states that leukoplakia is a predominantly white patch that cannot be characterized clinically or histopathologically as any other definable lesion Kramer et al.

In a study leukiplakia patients with OL, the authors reported that high-risk OL was associated with a 4.